română VIOREL VULTURESCU, ELENA DINU, VIRGINIA VULTURESCU
Abstract
Romania participates to the EU Programme since 1998, when the 5th Framework Programme included two new members (Romania and Bulgaria). Starting with 2007, Romania is equal in rights and obligations with other EU member states like Germany, Italy, France, etc.. Strong competition with European homologues, high quality standards imposed in these projects, lack of international visibility as well as links with scientific communities from EU member states, led to a poor performance of Romanian participants.
This paper presents the evolution of Romanian participation to the EU Framework programme and an analysis of ”macromaterials and nanomaterials” area where Romanian scientific community performed at EU average or above. This area is one of those where it has been also well performed to other European instruments (ex. MANUNET), it could be considered as a working base for a future national strategy for research (after 2020), where performance in some areas and fund raising from European and international sources should determine public allocation for research, technological development and innovation. There are also presented those measures to be taken, in order to fulfill its commitments from EU 2020 Strategy.
Keywords
EU, Research Framework Programmes, Romanian participation, micro and nano-materials field
M.M. MARIN, M.G. ALBU KAYA, A. FICAI, M.V. GHICA, L. POPA, R. ȚUȚUIANU
Abstract
Gastric ulcer disease is a common problem of the gastro-intestinal tract with its increasing incidence and prevalence attributed to the loss of balance between aggressive and protective factors. The purpose of this study was to obtain and characterize biomaterials for the regeneration of the soft tissue of the digestive system. Powders with different concentrations of collagen hydrolysate, zeolite and propolis were obtained by lyophilization. The type I collagen hydrolysate was obtained by acidic hydrolysis. A stable DPPH radical was used for determination of the free radical scavenging activity of the propolis. The morphology (Scanning Electron Microscopy – SEM), the spectral characteristics (Fourier Transform Infrared Spectroscopy – FT-IR, X ray diffraction – XRD), the goniometry (contact angle), in vitro assessment to simulated gastric acid and the biocompatibility (XTT assay) of the designed powders were studied. The collagen hydrolysate, zeolite and propolis biomaterials exhibited characteristics that make them potential candidates for use in the treatment of gastric ulcer.
Keywords
Collagen hydrolysate, zeolite, propolis, gastric ulcer
IZABEL BOTA, ROXANA POPESCU, CAIUS SOLOVAN
Abstract
Autolog platelet concentrate, a therapeutic procedure that is obtained from preparation of platelet rich plasma (PRP), has gained a lot of popularity especially in treatment of diverse aesthetic procedures. The plasma concentrate contains diverse cytokines and growth factors including tumor necrosis growth factors-α (TNF-α), transforming growth factors (TGF), platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and epithelial growth factor (EGF). The active byproduct obtained through this technique play a great role in many processes from stimulating angiogenesis all the way to healing tissue damage.
This study was conducted in order to compare growth factor levels obtained from PRP concentrate from subjects with different skin photo-type: II, III, and IV Fitzpatrick scale. Fresh whole blood was drawn from 20 healthy donors, age from 19 to 42. Plasma was separated by double spin technique, since it results in a higher platelet concentration, activated with Sodium Citrate 3.2% in polypropylene plastic tube. The platelet concentrate was evaluated with enzyme-linked immunosorbent assay (ELISA).
Based on our results, we demonstrated that selected cytokines are present in platelet-rich plasma and that these concentrates of growth factor profile is not influenced by skin photo-type.
Keywords
growth factors, cytokines, enzyme-linked immunosorbent assay (ELISA), Platelet-Rich Plasma (PRP)
NICUȘOR BAROIU , LILIANA BAROIU, VIRGIL GABRIEL TEODOR, LUCIAN TOMA CIOCAN
Abstract
Super hard tungsten carbide dental fissure bur for cutting dental crowns of carbide has a longer lifetime than regular carbide millings and minimize the risk of fractures, due theirs concentricity. From the perspective of tooth geometry, in this case a smaller cutting angle, they assure a smoother and more efficient cutting.
Such geometry requires accurate, fast and efficient helical flute profiling methods of profiling, given also the diminished dimensions of such dental tools.
The profiling of side mill which generate helical flute of the dental crosscut bur may be done using analytical methods: Gohman or Nikolaev. In this paper, it is proposed a graphical method, the method of “substitutive circles” for profiling of side mill which generate a helical flute of the dental bur.
In order to prove the accuracy of the method it is proposed the check of the axial profile of the side mill by an analytical method completed with a numerical example of the form and coordinates of the tool’s axial section.
The proposed method, developed in the CATIA graphical design environment is characterized by the simplicity and accuracy for profile determination. The method is also very intuitive.
Keywords
CAD profiling method, side mill, helical surfaces, dental bur
ELENA-INES ADAM-DIMA, MIHAELA ILIE, CARMEN PURDEL
Abstract
Decrease of the oxidative stress represents a major challenge in current therapy. Among up-to-date approaches, the use of nanoparticles as carriers of antioxidants has been intensively studied. One special case is the use of selenium nanoparticles (SeNPs), as selenium, an essential micronutrient for animals and humans, can act by itself as a good radical scavenger. This paper reviews the current trends for using SeNPs in therapy, describing shortly the major SeNPs preparation and characterisation methods, their in vitro and in vivo effects and their possible therapeutical use. The mechanisms underlying the effects of SeNPs are shortly connected with their beneficial / toxicological risk ratio.
Keywords
selenium, nanoparticles, antioxidant, oxidative stress, effects, toxicity, therapy
CRISTINA BUSUIOC, IZABELA CONSTANTINOIU, MONICA ENCULESCU, MIHAELA BEREGOI, SORIN - ION JINGA
Abstract
Ceramic thin films belonging to SiO2–P2O5–CaO–MgO–ZnO–CaF2 system were obtained by combining the sol-gel approach with the spin coating technique. Titanium plates were employed as substrates. The deposited coatings were characterized in terms of composition, structure and morphology with the help of the following methods: X-ray diffraction, Fourier - transform infrared spectroscopy and scanning electron microscopy coupled with energy - dispersive X-ray spectroscopy. In order to assess the bioactivity of a potential metallic implant covered with such layers, the samples were immersed in simulated body fluid for 14 days and their surface was investigated. The results showed that the thin films calcined at a lower temperature have a better biological response due to the vitroceramic nature.
Keywords
Ceramics; Thin films; Sol-gel; Spin coating; Medical implants
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Year
2018
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Issue
48 (4)
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Pages
401-406
DANIELA VRÎNCEANU, BOGDAN BĂNICĂ, CĂTĂLIN FLORIN CÎRSTOIU, RALUCA PAPACOCEA, TOMA PAPACOCEA
Abstract
The orbital floor has several anatomical features which are essential during reconstruction. The task of reconstructing the orbital floor wall is difficult and usually exist an important discrepancy between the shape of the implant to be inserted and the anatomical three dimensional shape of the orbital wall. We present the case of a 25 years old woman, with a left orbital fracture after domestic assault; for the reconstruction of the defect from left orbital floor, we used a Matrix Orbital plate, with minima adjustments to the length of the plate, not to the predesigned contour. The follow up extended 6 months after the titanium implant with excellent biocompatibility. The Matrix Midface Preformed orbital plate has the advantage of insertion without contouring, except bending and trimming of the fixation holes, thus is more independent on experience of the surgeon.
Keywords
titanium, implants, orbital floor, fracture, reconstruction
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Year
2018
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Issue
48 (4)
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Pages
407-411
ENIKÖ VOLCEANOV, CRISTINA GEORGIANA POPA, ADRIAN VOLCEANOV, SORIN CIUCĂ
Abstract
Alumina and zirconia-based ceramics present reduced wear rates and excellent long-term biocompatibility, which can increase the longevity of the implants. In this study, the effects of simultaneous admixture of CaO and MgO on the crystalline phases, crystallite sizes and sintering properties of coprecipitated Al2O3-ZrO2 powder are investigated using complex thermal analysis (TG, DTA, DTG), X-ray diffractometry (XRD), scanning electron microscopy (SEM) coupled with EDS.
Correlations among composition - microstructure and properties of the coprecipitated Al2O3-ZrO2 powder after sintering at 1050 °C, 1350 °C, and 1500 °C with 2 hours soaking time at each temperature were performed. The results showed that development of tetragonal and cubic phase of zirconia stabilized with Ca2+ and Mg2+ was effective at 1350°C and 1500 °C respectively. In dental applications, dental materials are soaked in saliva, which contains a large number of ions which in turn may accelerate the corrosion of materials. In such context, the chemical stability in modified Fusayama-Meyer type artificial saliva of sintered alumina – zirconia ceramics was also investigated. The ceramic samples sintered at 1500 °C show a better chemical stability, as the pH variation is lower when using a starting immersion solution with pH = 7.4. However, the variation of pH after immersion in artificial saliva is obvious after 216-288 hours due to the ionic transport between ceramic and the solution, even after sintering at 1500 °C
Keywords
Zirconia Thoughned Alumina, bioceramic, chemical stability, artificial saliva
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Year
2018
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Issue
48 (4)
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Pages
412-421